Earl Fu Selected Research

Gingival Overgrowth

4/2021	Antioxidants protect against gingival overgrowth induced by cyclosporine A.
1/2015	Role of Shh and TGF in cyclosporine-enhanced expression of collagen and α-SMA by gingival fibroblast.
3/2013	Can chlorhexidine mouthwash twice daily ameliorate cyclosporine-induced gingival overgrowth?
1/2013	Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts.
5/2006	Cyclosporin-induced downregulation of the expression of E-cadherin during proliferation of edentulous gingival epithelium in rats.
4/2006	Upregulation of the expression of epidermal growth factor and its receptor in gingiva upon cyclosporin A treatment.
12/2005	Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor gene and protein expression in cyclosporin-induced overgrown edentulous gingiva in rats.
12/2005	Effect of cyclosporin A on the expression of inducible nitric oxide synthase in the gingiva of rats.

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Earl Fu Research Topics

Disease

12	Neoplasms (Cancer) 10/2018 - 01/2005
10	Periodontitis 02/2022 - 10/2013
8	Gingival Overgrowth 04/2021 - 12/2005
7	Inflammation (Inflammations) 03/2021 - 12/2005
5	Mouth Neoplasms (Oral Cancer) 10/2018 - 10/2009
4	Wounds and Injuries (Trauma) 03/2021 - 04/2013
3	Chronic Periodontitis 01/2021 - 06/2017
3	Alveolar Bone Loss 01/2019 - 01/2014
2	Osteonecrosis (Kienbock's Disease) 12/2019 - 10/2014
2	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 05/2011
2	Thyroid Neoplasms (Thyroid Cancer) 01/2017 - 05/2016
2	Periodontal Diseases (Periodontal Disease) 10/2016 - 10/2013
2	Bone Resorption 03/2016 - 05/2002
2	Breast Neoplasms (Breast Cancer) 11/2015 - 12/2014
2	Squamous Cell Carcinoma of Head and Neck 01/2012 - 08/2010
2	Atypical Squamous Cells of the Cervix 04/2005 - 10/2003
1	Peri-Implantitis 07/2022
1	Denture Stomatitis 06/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Ovarian Neoplasms (Ovarian Cancer) 07/2017
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Skin Neoplasms (Skin Cancer) 01/2017
1	Body Weight (Weight, Body) 01/2017
1	Anaplastic Thyroid Carcinoma 05/2016
1	Obesity 05/2016
1	Parkinson Disease (Parkinson's Disease) 01/2016

Drug/Important Bio-Agent (IBA)

9	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2021 - 12/2005
9	Proteins (Proteins, Gene)FDA Link 03/2021 - 12/2005
5	Messenger RNA (mRNA)IBA 10/2018 - 01/2005
4	CytokinesIBA 03/2021 - 01/2014
4	ResveratrolIBA 01/2018 - 12/2014
4	Matrix Metalloproteinases (MMPs)IBA 10/2016 - 10/2013
3	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2021 - 11/2015
3	leptin (116-130)IBA 07/2017 - 05/2016
3	LeptinIBA 07/2017 - 05/2016
3	Immunosuppressive Agents (Immunosuppressants)IBA 03/2013 - 06/2010
3	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2012 - 10/2003
2	TitaniumIBA 07/2022 - 04/2013
2	CateninsIBA 01/2018 - 03/2015
2	IntegrinsIBA 01/2018 - 12/2014
2	Peptides (Polypeptides)IBA 07/2017 - 01/2017
2	ChlorhexidineIBA 06/2017 - 03/2013
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2016 - 12/2005
2	LipopolysaccharidesIBA 03/2016 - 05/2002
2	Cyclin D1IBA 03/2015 - 05/2006
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 03/2015 - 05/2006
2	Cadherins (E-Cadherin)IBA 03/2015 - 05/2006
2	Indicators and Reagents (Reagents)IBA 08/2010 - 04/2005
2	Biomarkers (Surrogate Marker)IBA 04/2005 - 10/2003
1	Silk FDA Link 02/2022
1	AntioxidantsIBA 04/2021
1	SiliconesIBA 03/2021
1	Conditioned Culture MediaIBA 03/2021
1	Oxygen (Dioxygen)IBA 12/2019
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2019
1	Zoledronic Acid (Zometa)FDA Link 12/2019
1	flavanoneIBA 01/2019
1	HesperidinIBA 01/2019
1	Thyroid HormonesIBA 10/2018
1	B7-H1 AntigenIBA 10/2018
1	nano-diamino-tetracIBA 10/2018
1	Biocompatible Materials (Biomaterials)IBA 02/2018
1	ChitosanIBA 02/2018
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2018
1	Hormones (Hormone)IBA 01/2018
1	Dental Implants (Dental Implant)IBA 01/2018
1	tetraiodothyroacetic acid (TA(4))IBA 01/2018
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2018
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2017
1	Follicle Stimulating Hormone (Follitropin)FDA Link 07/2017
1	Antineoplastic Agents (Antineoplastics)IBA 07/2017
1	Sulfur Compounds (Compounds, Sulfur)IBA 06/2017
1	Sulfides (Thioethers)IBA 06/2017
1	Mitogen-Activated Protein KinasesIBA 01/2017
1	Vascular Endothelial Growth Factor CIBA 01/2017
1	carvacrolIBA 01/2017
1	Phenol (Carbolic Acid)FDA Link 01/2017
1	Monoterpenes (Monoterpenoids)IBA 01/2017
1	Plant ExtractsIBA 01/2017
1	AntigensIBA 09/2016
1	MucinsIBA 09/2016
1	Polysaccharides (Glycans)IBA 09/2016
1	Tn antigenIBA 09/2016
1	CarbohydratesIBA 09/2016
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 05/2016
1	Dental AmalgamIBA 01/2016
1	Beclin-1IBA 01/2016
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2016
1	Complex MixturesIBA 01/2016
1	Fulvestrant (Faslodex)FDA Link 11/2015
1	Dihydrotestosterone (Androstanolone)IBA 11/2015
1	Caspase 3 (Caspase-3)IBA 11/2015

Therapy/Procedure

8	Therapeutics 01/2021 - 06/2010
7	Ligation 01/2019 - 10/2013
2	Tooth Extraction (Tooth Extractions) 12/2019 - 10/2014
2	Low-Level Light Therapy (LLLT) 01/2016 - 11/2015
1	Sutures (Suture) 02/2022
1	Oral Administration 01/2019
1	Dentures 06/2018
1	Injections 03/2016